The least frequent sign/symptom was hemoptysis (1.65%). Only one study reported dermatological manifestations. In percentage terms, 6 symptoms had a general prevalence greater than or equal to 25%, namely, fever (58.66%), cough (54.52%), dyspnea (30.82%), malaise (29.75%), fatigue (28.16%) and sputum/secretion (25.33%). ![]() The 152 publications finally included a total of 41,409 individuals from at least 23 countries and 26 different clinical manifestations were reported. After complete reading, 32 studies that did not report clinical manifestations were excluded. Among the studies, 184 met the initial inclusion criteria, with a total of 114,046 patients. A total of 8070 scientific productions were found in the databases. ![]() A systematic review of the literature was conducted. This study aimed to systematize the literature regarding clinical manifestations of patients with confirmed COVID-19. ![]() ![]() Clinical manifestations of COVID-19 are varied in the general population.
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